摘要 |
Compositions and methods for modifying therapeutics with activated polyoxyalkylenes are provided. Therapeutics that may be modified contain or are derivatized to contain an amino or nucleophilic group. Therapeutics include peptides, proteins, nucleic acids, and the like. In addition, cationic peptides, modified or unmodified, can be used to treat tumors, either alone or in combination with a conventional antineoplastic agent. |
申请人 |
MICROLOGIX BIOTECH INC.;FRIEDLAND, HILLEL, DAVID;KRIEGER, TIMOTHY, J.;TAYLOR, ROBERT;ERFLE, DOUGLAS;FRASER, JANET, R.;WEST, MICHAEL, H., P. |
发明人 |
FRIEDLAND, HILLEL, DAVID;KRIEGER, TIMOTHY, J.;TAYLOR, ROBERT;ERFLE, DOUGLAS;FRASER, JANET, R.;WEST, MICHAEL, H., P. |