ORAL MUCOADHESIVE COMPOSITIONS CONTAINING GASTROINTESTINAL ACTIVES

摘要

The present invention relates to mucoadhesive compositions comprising a safe and effective amount of a gastrointestinal active; from about 1.5 % to about 10 %, by weight of the composition, of a clay component; and from about 0.01 % to about 1 %, by weight of the composition, of a gum component. Alternativel y, the clay component can be a titanium dioxide or a silicone dioxide component . The mucoadhesive compositions also preferably comprise up to about 2 % by weight of the composition, of a non-ionic component such as methyl cellulose . The present invention also relates to methods of prevention and treatment of gastrointestinal tract disorders in humans or lower animals by orally administering a composition of the present invention.