7-(2-IMIDAZOLYNYL AMINO) QUINOLINIC COMPOUNDS USEFUL AS ANTAGONISTS OF A- 2-ADRENORECEPTORS

摘要

The subject invention involves methods of treating nasal congestion comprising administration, to a human or lower animal in need of such treatment of a safe and effective amount of a compound having the following structure: wherein: (a) R is unsubstituted C1-C3 alkanyl or alkenyl; and (b) R' is selected from hydrogen; unsubstituted C1-C3 alkanyl or alkenyl; unsubstituted C1-C3 alkylthio or alkoxy; hydroxy; thiol; cyano; and halo. The subject invention also involves the use of such compounds for preventing or treating other respiratory, ocular and/or gastrointestinal disorders. The subject invention also involves novel compounds having the above structure wherein R' is hydrogen or fluoro or cyano.