| 摘要 |
PROBLEM TO BE SOLVED: To efficiently purify a dihalotrifluoroacetone derivative useful as an intermediate for medicines and agrochemicals by converting the dihalotrifluoroacetone derivative into a derivative having a higher boiling point, purifying the resultant derivative by distillation and then dehydrating and returning the purified derivative again to the dihalotrifluoroacetone derivative. SOLUTION: (A) A dihalotrifluoroacetone derivative represented by formula I (X is a halogen other than fluorine) (e.g. 1,1-dichloro-3,3,3-trifluoroacetone) is reacted with water and converted into (B) a dihalofluoropropanediol represented by formula II (e.g. 1,1-dichloro-3,3,3-trifluoro-2,2-propanediol) or its hydrate, which is then distilled to dehydrate the component B. Thereby, the component A is purified. Furthermore, e.g. hydrochloric acid is preferably employed as an acid used for the dehydration and the reaction is preferably carried out in an organic solvent such as benzene usually at a temperature of 0 deg.C to about the boiling point of the solvent.
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