发明名称 ROC method for early detection of disease
摘要 A method of assessing risk of an individual for a disease is disclosed. A level of a marker for the disease is detected, and the risk of disease is computed from a statistical analysis of the marker level distributions for tested normal and diseased populations, using multivariate distributions. The computed risk is compared to thresholds to triage the individual into a normal, borderline, or elevated risk group, and a course of action based on the risk group is determined. Memory storing a program for execution on a data processing system, as well as a computer system comprising said memory is also disclosed, the memory comprising a receiver for signals representative of levels of a marker for the disease; a central processing unit for computing risk of disease from one or more levels of the marker, and for comparing the computed risk to thresholds to triage the individual; and storage medium for the marker levels for subsequent computations of risk of disease.
申请公布号 US6030341(A) 申请公布日期 2000.02.29
申请号 US19980139088 申请日期 1998.08.24
申请人 THE GENERAL HOSPITAL CORPORATION 发明人 SKATES, STEVEN J.;JACOBS, IAN;KNAPP, ROBERT
分类号 A61B5/00;G01N33/574;(IPC1-7):A61B5/00 主分类号 A61B5/00
代理机构 代理人
主权项
地址