PERCUTANEOUS ABSORPTION PATCH

摘要

PROBLEM TO BE SOLVED: To produce a percutaneous absorption patch excellent in transdermal absorption of estradiol by employing an ester of estradiol. SOLUTION: When percutaneous absorption patch has a medicament-including layer, where medicament and percutaneous absorbefacient are uniformly included in base matrix, on one surface of a support, the medicament is estradiol-17β-valeric acid ester and percutaneous absorbefacient is isopropyl myristate in a content of 5-40 w/w% based on the weight of the medicament-including layer. The medicament-including layer virtually include neither 1-8C aliphatic alcohol nor polyethylene glycol.