发明名称 |
Peptides peptide analogs peptidomimetics and other small molecules useful for inhibiting the activity of ribonucleotide reductase |
摘要 |
The invention relates to compositions which are useful for inhibiting ribonucleotide reductase enzymes, including the mammalian ribonucleotide reductase enzyme. The compositions include, but are not limited to, linear peptides, cyclic peptides, peptide analogs, and peptidomimetics. Methods of using the compositions of the invention to treat cancer and viral and bacterial infections are disclosed.
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申请公布号 |
US6030942(A) |
申请公布日期 |
2000.02.29 |
申请号 |
US19980040216 |
申请日期 |
1998.03.17 |
申请人 |
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA |
发明人 |
COOPERMAN, BARRY S.;HIRSCHMANN, RALPH F.;SMITH, III, AMOS B.;LAUB, PAUL;SASHO, SETSUYA;SPRENGELER, PAUL A.;BARWIS, BARI A.;FISHER, ALISON;NAIR, SHRIKUMAR |
分类号 |
A61K38/00;C12N9/02;(IPC1-7):A61K38/00;A61K38/12;A61K38/16 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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