| 发明名称 |
Antisense inhibition of PEPCK-mitochondrial expression |
| 摘要 |
Antisense compounds, compositions and methods are provided for modulating the expression of PEPCK-mitochondrial. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding PEPCK-mitochondrial. Methods of using these compounds for modulation of PEPCK-mitochondrial expression and for treatment of diseases associated with expression of PEPCK-mitochondrial are provided.
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| 申请公布号 |
US6030837(A) |
申请公布日期 |
2000.02.29 |
| 申请号 |
US19990366257 |
申请日期 |
1999.08.03 |
| 申请人 |
ISIS PHARMACEUTICALS INC. |
发明人 |
MCKAY, ROBERT;BUTLER, MADELINE M.;COWSERT, LEX M. |
| 分类号 |
C12N15/09;A61K9/10;A61K31/7088;A61K38/00;A61K48/00;A61P3/00;A61P3/02;A61P3/10;A61P43/00;C12N15/113;(IPC1-7):C12Q1/68;C07H21/04;C12M15/00 |
主分类号 |
C12N15/09 |
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