发明名称 BIPODAL LIGAND-METAL ION CHELATES
摘要 The invention relates to complexes comprising a metal ion and chelating ligands which incorporate a bipodal backbone. More particularly, the invention pertains to bipodal ligand bis-{¢bis-(carboxymethyl)-amino!-methyl}-phosphinic acid (H5xuta) which forms novel coordination compounds with a variety of metal ions, particularly, but not exclusively, trivalent metal ions and lanthanide metal ions, which are useful in nuclear medicine. The process comprises complexing Tc or Re or any one of the group 13 metals, Al, Ga and In, and any one of the rare earths, Sc, Y, La, Ce, Pr, Nd, Pm, Sm, Eu, Gd, Tb, Dy, Ho, Er, Tm, Yb and Lu, with the H5xuta bipodal ligand.
申请公布号 CA2246204(A1) 申请公布日期 2000.02.29
申请号 CA19982246204 申请日期 1998.08.31
申请人 THE UNIVERSITY OF BRITISH COLUMBIA 发明人 ORVIG, CHRIS;XU, LIANG
分类号 A61K49/10;C07F9/30;C07F13/00;(IPC1-7):C07F9/30;A61K49/00;A61K51/04 主分类号 A61K49/10
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