发明名称 METHOD FOR DETERMINING ONE OR MORE TYPES OF HEPATITIS C VIRUS
摘要 According to the invention the method comprises the following steps: a) providing a biological sample from a person presumably infected with the hepatitis C virus; b) contacting the sample with a reagent comprising a combination of type specific epitopes specific for the hepatitis C virus, at least one epitope of the combination originating in the hepatitis C virus non-structural 4 region and moreover, the contact being achieved under conditions which allow the formation of the first epitope - antibody complexes; and c) assaying for the presence of the epitope - antibody complexes in the sample in order to determine whether the antibodies in the sample bind themselves to the first reagent Additionally, the method also comprises the following steps: d) contacting the sample with a second reagent-type specific epitope specific for the hepatitis C virus, said epitope originating in the hepatitis C virus core region and, moreover, the contact being achieved under conditions which allow the formation of a second epitope - antibody complex; and d) assaying for the presence of the second epitope - antibody complex in the sample in order to determine whether the antibodies in the sample bind themselves to the second reagent
申请公布号 RO115471(B1) 申请公布日期 2000.02.28
申请号 RO19950001952 申请日期 1994.05.09
申请人 CHIRON CORPORATION, EMERYVILLE, CALIFORNIA 发明人 CHIEN DAVID Y;KUO GEORGE
分类号 A61K39/29;C07K14/18;C12N15/09;C12N15/40;G01N33/576;(IPC1-7):G01N33/576 主分类号 A61K39/29
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