| 发明名称 |
PROCESS FOR PRODUCING PURIFIED ASIALOGLYCOPROTEINS FROM HEPATITIS C VIRUS |
| 摘要 |
The invention relates to a process of producing purified asialoglycoproteins, derived from hepatitis C virus, comprising growing, on a suitable culture medium, a host-cell changed with a structural gene encoding a HCV asialoglycoprotein selected from the group E 1 and/or E 2, inducing the structural gene expression under the conditions which favour the inhibition of sialylation and the isolation of the asialoglycoproteins obtained by coupling with a lectine capable of binding the terminal mannose
|
| 申请公布号 |
RO115446(B1) |
申请公布日期 |
2000.02.28 |
| 申请号 |
RO19930000626 |
申请日期 |
1991.11.07 |
| 申请人 |
CHIRON CORPORATION, EMERYVILLE |
发明人 |
RALSTON O ROBERT;MARCUS FRANK;THUDIUM B KENT;GERVASE A BARBARA;HALL A JOHN |
| 分类号 |
G01N33/576;A61K31/00;A61K38/00;A61K39/00;A61K39/29;A61P31/00;A61P31/12;A61P37/02;C07K1/16;C07K1/22;C07K9/00;C07K14/00;C07K14/18;C07K14/42;C07K16/00;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/00;C12N15/09;C12N15/51;C12P21/02;C12R1/91;C12R1/93;G01N33/53;(IPC1-7):C07K9/00;A61K37/10 |
主分类号 |
G01N33/576 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
