| 摘要 |
A block polymer having functional groups at both ends of its molecule and comprising hydrophilic/hydrophobic segments. As the functional groups at both ends, the polymer carries amino, carboxy or mercapto at the 'alpha'-end and hydroxy, carboxy, aldehyde, vinyl, etc. at the 'omega'-end. The hydrophilic segment comprises polyoxyethylene while the hydrophobic segment is one derived from lactide, lactone or (meth)acrylate. This block polymer forms a polymeric micelle and is applicable to biocompatible materials, etc. A block polymer which is represented by formula X-O-(CH2CH2O)m-(Y)n-Z Where X denotes alkyl group 1-10 carbon atoms with one or two constituents consisting of amino group blocked with amino protecting group, carboxy group protected with carboxyl protecting group. Y denotes a group selected from formula (I) Z denotes functional groups selected from hydrogen, CH2=CH-CO, CH2C(CH3)-CO-, CH2=CH-CH2-, p-toluensulfonyl group, mercapto group, alkyl group (C1-5) m and n independently denote an integer of 2-10,000
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