发明名称 AGENT FOR DIAGNOSIS OF EXTERNAL SECRETION FUNCTION OF PANCREAS
摘要 PROBLEM TO BE SOLVED: To provide an agent for the diagnosis of external secretion function of pancreas enabling the quick and precision examination of the external secretion function of pancreas in high sensitivity while reducing the load on the examinee. SOLUTION: This agent for the diagnosis of external secretion function of pancreas contains an amino acid, a peptide or their pharmacologically permissible salt containing at least one 13C or 14C (excluding Bz-Tyr-13C-PABA) is provided. The present invention further provides a 13C- or 14C-labeled compound expressed by the following formula or their salts. Formula: X2-R2-Y2-Z1 (X2 is H or a protecting group; R2 is a peptide having an amino acid number of 2-5, an amino acid or a single bond; Y2 is an amino acid; Z1 is a (protected) amino acid; when X2, Z1 and the amino acid in R2, Y2 and Z1 are carbon- containing protecting groups, at least one of the protecting groups is labeled with 13C or 14C).
申请公布号 JP2000053697(A) 申请公布日期 2000.02.22
申请号 JP19990149496 申请日期 1999.05.28
申请人 TOKYO GAS CO LTD 发明人 KONO TADASHI;HOSOI GOSABURO;OSHIMA JUNKO;SHIBATA KUNIHIKO;ITOU ASUKA
分类号 A61K49/00;A61K49/18;A61K51/08;A61K51/12;C07K5/062;C07K5/065;C07K5/068;C07K7/06;C07K14/00;G01N33/497;(IPC1-7):C07K5/065 主分类号 A61K49/00
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