发明名称 STABLE INJECTABLE PHARMACEUTICAL FORMULATION FOR FOLIC ACID AND LEUCOVORIN SALTS AND METHOD
摘要 Injectable aqueous compositions comprising folic acid and leucovorin and their salts, optionally including benzyl alcohol, sodium chloride and agents for adjusting pH are stabilized and buffered in the range of 6 to 10 by adding a combination of tromethamine and monothioglycerol. Such compositions remain stable for prolonged periods even when exposed to sunlight:
申请公布号 CA2023563(C) 申请公布日期 2000.02.22
申请号 CA19902023563 申请日期 1990.08.17
申请人 发明人 HAEGER, BRUCE E.
分类号 A61K9/08;A61K9/00;A61K31/505;A61K47/00;A61K47/10;A61K47/18;A61K47/20;A61P3/02;(IPC1-7):A61K47/20 主分类号 A61K9/08
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