摘要 |
This invention relates to novel sequence and polymorphisms in the human neurokinin 2 receptor (NK2R) gene, including its promoter region. The invention also relates to methods and materials for analysing allelic variation in the NK2R gene and its promoter region, and to the use of NK2R polymorphism in the diagnosis and treatment of NK2R ligand-mediated diseases such as asthma, depression, anxiety, emesis and urinary incontinence. |