发明名称 Vaccine.
摘要 The present invention relates to fusions proteins, comprising a protein or part of a protein that provides T helper epitopes and an antigen from a human-papilloma virus. In particular the invention relates to fusion proteins comprising an E6 or E7 protein from HPV strain 16 or 18 linked to protein D from Haemophilus influenza B. The invention also provides vaccine compositions that are useful in the treatment or prophylaxis of human papilloma induced tumors.
申请公布号 ZA9807591(B) 申请公布日期 2000.02.21
申请号 ZA19980007591 申请日期 1998.08.21
申请人 SMITHKLINE BEECHAM BIOLOGICALS S.A. 发明人 CLAUDINE BRUCK;TERESA CABEZON SILVA;ANNE-MARIE EVA FERNANDE DELISSE;CATHERINE MARIE GHISLAINE GERARD;ANGELA LOMBARDO-BENCHEIKH
分类号 C12N15/09;A61K9/107;A61K39/00;A61K39/12;A61K39/145;A61K39/39;A61P31/12;A61P35/00;A61P37/00;C07K14/025;C07K19/00;C12N1/15;C12N1/19;C12N1/21;C12N5/02;C12N5/10;C12P21/02 主分类号 C12N15/09
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