| 发明名称 |
Slapekli saturosi heteroaromatiski savienojumi ka xa faktora inhibitori |
| 摘要 |
The present invention provides novel methods for the asymmetric synthesis of (S)-6-chloro-4-cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-2H-3,1 -benzoxazin-2-one of formula (VI-i) which is useful as a human immunodeficiency virus (HIV) reverse transcriptase inhibitor.
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| 申请公布号 |
LV12430(A) |
申请公布日期 |
2000.02.20 |
| 申请号 |
LV19990000099 |
申请日期 |
1999.07.30 |
| 申请人 |
DUPONT PHARMACEUTICALS COMPANY |
发明人 |
DONALD JOSEPH-PHILLIP PINTO;JAMES RUSSELL PRUITT;JOSEPH CACCIOLA;JOHN MATTHEW FEVIG;QI HAN;MICHAEL JAMES ORWAT;MIMI LIFEN QUAN;KAREN ANITA ROSSI |
| 分类号 |
A61K31/40;A61K31/41;A61K31/4155;A61K31/4164;A61K31/4178;A61K31/4184;A61K31/4192;A61K31/427;A61K31/4439;A61K31/454;A61K31/496;A61K31/506;A61K31/5377;A61P7/02;A61P43/00;C07D207/34;C07D231/14;C07D231/16;C07D231/18;C07D231/40;C07D231/42;C07D233/90;C07D249/06;C07D249/10;C07D257/04;C07D401/04;C07D401/12;C07D403/12;C07D409/12;C07D413/12;C07D417/12;C07D521/00;(IPC1-7):C07D207/34 |
主分类号 |
A61K31/40 |
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