CHIMERIC ADENOVIRAL VECTORS FOR TARGETED GENE DELIVERY
摘要
The present invention provides chimeric adenoviral vectors that preferentially infect a target mammalian cell. Also provided are methods of targeting gene delivery to a specific cell type, treatment of cancer and methods of inducing a specific immune response in a subject. Pharmaceutical compositions are also provided.
申请公布号
WO9947180(A9)
申请公布日期
2000.02.17
申请号
WO1999US06101
申请日期
1999.03.19
申请人
GENZYME CORPORATION;SHANKARA, SRINIVAS;ARMENTANO, DONNA;ROBERTS, BRUCE, L.
发明人
SHANKARA, SRINIVAS;ARMENTANO, DONNA;ROBERTS, BRUCE, L.