| 摘要 |
The invention provides adhesive matrix type transdermal patches and methods for manufacturing the patches. More specifically, the invention utilizes ordinary, prefabricated, commercially available, pressure-sensitive adhesive tapes with skin compatible adhesives, as the structural part of the patch. The adhesive matrix layer of the tape is loaded with the desirable active substances either by embedding, in the case of powders, the active substances in an adhesive matrix layer by the application of heat or pressure, or by a diffusion process for active substances comprising liquids/semi-liquids are carried depressions in located in an embossed release liner or backing layer, which are contact laminated to the adhesive matrix by pressure, or by the utilizing of conventional printing processes to print a half-tone pattern of a bioactive liquid on the adhesive matrix.
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