Process for the preparation of acetic esters from methanol

摘要

Acetic ester is produced economically by a gas phase carbonylation of methanol with carbon monoxide followed by a transesterification. Specifically, the inventive process comprises (a) carbonylating methanol in a gas phase with carbon monoxide to produce a mixture of acetic acid and methyl acetate; (b) separating from the production mixture the acetic acid, and a mixture of the methyl acetate and the co-catalyst; (c) further separating said methyl acetate and the co-catalyst and recycling the separated co-catalyst to the carbonylation reactor; (d) introducing the separated methyl acetate into a lower region of a transesterification reactor at a temperature of above its boiling point; (e) introducing an C2 or higher alcohol into an upper region of the trans-esterification reactor at a temperature of up to its boiling point; (f) transesterifying the methyl acetate with the alcohol in the presence of an acid catalyst to produce a mixture containing acetic esters; and (g) recovering the acetic esters from the mixture as a bottom product while recycling the unreacted methyl acetate and methanol to the carbonylation reactor or distillation column.