| 发明名称 |
URATE OXIDASE |
| 摘要 |
The present invention relates, in general, to urate oxidase (uricase) proteins and nucleic acid molecules encoding same. In particular, the invention relates to uricase proteins which are particularly useful as, for example, intermediates for making improved modified uricase proteins with reduced immunogenicity and increased bioavailability. |
| 申请公布号 |
WO0008196(A2) |
申请公布日期 |
2000.02.17 |
| 申请号 |
WO1999US17678 |
申请日期 |
1999.08.05 |
| 申请人 |
DUKE UNIVERSITY;HERSHFIELD, MICHAEL;KELLY, SUSAN, J. |
发明人 |
HERSHFIELD, MICHAEL;KELLY, SUSAN, J. |
| 分类号 |
C12N15/09;A61K38/00;A61K38/44;A61K38/54;A61K48/00;A61P19/06;C07H21/04;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N9/06;C12N15/00;(IPC1-7):C12N9/09 |
主分类号 |
C12N15/09 |
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