发明名称 Photocleavable and acid cleavable linkers for combinatorial chemistry
摘要 A substrate for solid phase synthesis comprising a solid phase-linker combination of the formula I is disclosed. Also disclosed are processes for preparing the substrate and chemical intermediates useful therein. Among the novel intermediates are compounds of the formula II wherein R1 is -NO2 or -CHO; R2 is -OCH3, -CHO or -H; R3 is chosen from the group consisting of hydroxyl, the residue of a solid support having a plurality of amino groups, and the residue of an ester, and n=1 or 3.A substrate of solid phase synthesis of the formula III is also disclosed.
申请公布号 AU5127399(A) 申请公布日期 2000.02.14
申请号 AU19990051273 申请日期 1999.07.22
申请人 PHARMACOPEIA, INC. 发明人 VINH D. TRAN;VU VAN MA;RUIYAN LIU
分类号 C07B61/00;C07C59/74;C07C205/37;C07C205/44;C07C235/06;C08F8/28;C08F8/30 主分类号 C07B61/00
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