发明名称 |
DERIVATIVES OF AROMATIC AMINES ACTING AS NOS INHIBITORS |
摘要 |
Compounds represented by the general formula (1): <CHEM> (where R1 and R2 are typically a hydrogen atom; R3 and R4 are typically a hydrogen atom or a lower alkyl group; R5 is typically a hydrogen atom; X1, X2, X3 and X4 are typically a hydrogen atom or a lower alkoxy group; A is typically an optionally substituted pyridine ring; m and n are each 0 or 1) have an NOS inhibiting activity and are useful as therapeutics of cerebrovascular diseases and other pharmaceuticals. |
申请公布号 |
PL334304(A1) |
申请公布日期 |
2000.02.14 |
申请号 |
PL19970334304 |
申请日期 |
1997.12.24 |
申请人 |
CHUGAI SEIYAKU KK |
发明人 |
ESAKI TORU;MAKINO TOSHIHIKO;NISHIMURA YOSHIKAZU;NAGAFUJI TOSHIAKI |
分类号 |
C07C215/56;A61K31/137;A61K31/40;A61K31/44;A61K31/4965;A61K31/50;A61K31/505;A61P9/10;C07C209/10;C07C211/55;C07C211/56;C07C217/92;C07C229/58;C07C229/60;C07C271/20;C07C323/09;C07D207/34;C07D207/42;C07D213/74;C07D213/75;C07D213/76;C07D213/78;C07D213/80;C07D213/803;C07D213/82;C07D213/85;C07D231/14;C07D231/16;C07D237/12;C07D237/20;C07D237/24;C07D239/42;C07D241/16;C07D241/24;C07D263/48;C07D277/42;C07D521/00 |
主分类号 |
C07C215/56 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|