| 摘要 |
Amidinophenol derivatives of the formula (I) and acid-addition salts thereof (in which R1 and R2 are alkyl, alkoxy, acyl, halogen, nitro, benzoyl, COOR4: A is bond, alkylene, group of the formula (II): R3 is group of the formula (III), (IV)) (see formulas I, II, III, IV) have inhibitory activities on phospholipase A2 and proteases (especially trypsin), and are useful for the prevention and/or the treatment of inflammatory diseases, allergic diseases, disseminated intravascular coagulation, pancreatitis, severity in pancreatitis and multiple organ failure.
|
