发明名称 |
Prenatal risk assessment for fetal abnormalities using dimeric inhibin data |
摘要 |
Dimeric inhibin concentration can be used in the determination of the risk of a women carrying an unborn child affected by chromosomal abnormalities, e.g. Downs Syndrome. A method for antenatal screening for chromosomal abnormalities is carried out by measuring body fluid taken from a pregnant woman for the level of at least one marker or precursor or metabolite of the marker together with the gestational age of the woman are compared with reference values taken from women carrying fetuses with chromosomal abnormalities and/or women carrying normal fetuses, using dimeric inhibin as a marker. A second marker is the free beta subunit of human chorion gonadotropin. An apparatus for carrying out the method described comprises a computer with a means for comparing the values described.
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申请公布号 |
US6022695(A) |
申请公布日期 |
2000.02.08 |
申请号 |
US19950511942 |
申请日期 |
1995.08.07 |
申请人 |
JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. |
发明人 |
BEARD, ANDREW JONATHAN;DAWKES, ADRIAN CHARLES;DAVIES, CHRISTOPHER JOHN |
分类号 |
G01N33/50;G01N33/53;G01N33/68;G01N33/74;G01N33/76;(IPC1-7):G01N33/68 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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