Radiolabeled platelet GPIIb/IIIa receptor antagonists as imaging agents for the diagnosis of thromboembolic disorders
摘要
This invention provides novel radiopharmaceuticals that are radiolabeled cyclic compounds containing carbocyclic or heterocyclic ring systems which act as antagonists of the platelet glycoprotein IIb/IIIa complex; to methods of using said radiopharmaceuticals as imaging agents for the diagnosis of arterial and venous thrombi; to novel reagents for the preparation of said radiopharmaceuticals; and to kits comprising said reagents.
申请公布号
US6022523(A)
申请公布日期
2000.02.08
申请号
US19970999400
申请日期
1997.12.29
申请人
DUPONT PHARMACEUTICALS COMPANY
发明人
DEGRADO, WILLIAM FRANK;MOUSA, SHAKER AHMED;SWORIN, MICHAEL;BARRETT, JOHN ANDREW;EDWARDS, SCOTT DAVID;HARRIS, THOMAS DAVID;RAJOPADHYE, MILIND;LIU, SHUANG