发明名称 PROCESS FOR THE PREPARATION OF 4,6-DISUBSTITUTED 2-ISOCYANATOPYRIMIDINES AND THEIR USE AS INTERMEDIATES FOR ACTIVE COMPOUND SYNTHESES
摘要 The invention relates to isocyanates of formula (I), wherein X and Y as show n in formula (I) are defined according to Claim No. 1, which can be produced b y reacting a compound of formula (II) or the salts thereof, wherein X and Y ar e defined as in formula (I), with 1 to 6 mol of phosgene per 1 mol of the compound of formula (II), in the presence of 2 to 3.5 mole equivalents of a base per mol of the compound of formula (II) and in the presence of an aprot ic organic solvent. The reaction is carried out at a reaction temperature rangi ng from -30 to +60 ~C for the compound of formula (I). The compounds (I) can be converted into addition products such as carbamates, ureas, sulfonylureas, a nd corresponding products, e.g. herbicidal sulfonylureas, by reacting them with nucleophiles.
申请公布号 CA2338349(A1) 申请公布日期 2000.02.03
申请号 CA19992338349 申请日期 1999.07.13
申请人 AVENTIS CROPSCIENCE GMBH 发明人 LACHHEIN, STEPHEN;FORD, MARK JAMES
分类号 C07D239/52;A01N47/12;A01N47/36;A01P13/00;C07D239/47;C07D239/54;C07D239/545;C07D239/69;(IPC1-7):C07D239/54 主分类号 C07D239/52
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