发明名称 Verfahren zur Herstellung von 4,6-disubstituierten 2-Isocyanatopyrimidinen und ihre Verwendung als Zwischenprodukte für Wirkstoffsynthesen
摘要 The invention relates to isocyanates of formula (I), wherein X and Y as shown in formula (I) are defined according to Claim No. 1, which can be produced by reacting a compound of formula (II) or the salts thereof, wherein X and Y are defined as in formula (I), with 1 to 6 mol of phosgene per 1 mol of the compound of formula (II), in the presence of 2 to 3.5 mole equivalents of a base per mol of the compound of formula (II) and in the presence of an aprotic organic solvent. The reaction is carried out at a reaction temperature ranging from -30 to +60 DEG C for the compound of formula (I). The compounds (I) can be converted into addition products such as carbamates, ureas, sulfonylureas, and corresponding products, e.g. herbicidal sulfonylureas, by reacting them with nucleophiles.
申请公布号 DE19833007(A1) 申请公布日期 2000.02.03
申请号 DE19981033007 申请日期 1998.07.23
申请人 HOECHST SCHERING AGREVO GMBH 发明人 FORD, MARK JAMES;LACHHEIN, STEPHEN
分类号 C07D239/52;A01N47/12;A01N47/36;A01P13/00;C07D239/47;C07D239/54;C07D239/545;C07D239/69;(IPC1-7):C07D239/545;C07D239/42;A01N43/54 主分类号 C07D239/52
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