发明名称 |
GRANULE MODULATING HYDROGEL SYSTEM |
摘要 |
A naproxen once-a-day matrix tablet is described which is based on a compressed mixture of a controlled release component of said tablet that contains: (i) substantially homogeneous granules of naproxen or a pharmaceutically acceptable salt of naproxen and an organic acid which are prepared by a granulation process which uses a pharmaceutically acceptable film forming material as the binding material; (ii) a pharmaceutically acceptable hydrogel forming polymer; and (B) a coating on said compressed mixture which consists essentially of naproxen or a pharmaceutically acceptable salt thereof and a pharmaceutically acceptable film forming composition which allows for immediate release of naproxen.
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申请公布号 |
WO0004879(A1) |
申请公布日期 |
2000.02.03 |
申请号 |
WO1999US17128 |
申请日期 |
1999.07.23 |
申请人 |
ANDRIX PHARMACEUTICALS, INC. |
发明人 |
CHEN, CHIH-MING;JAN, STEVE;XIE, JIANBO |
分类号 |
A61K9/22;A61K9/24;A61K9/26;A61K31/192;(IPC1-7):A61K9/14 |
主分类号 |
A61K9/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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