FGF-BP PROMOTER SEQUENCES AS SENSORS OF DRUG EFFECTS

摘要

Nucleic acid sequences encoding FGF-BP promoters and methods of using these sequences as sensors of drug effects and oncogenic, angiogenic, vascular, and immune function are described. Additional methods using the sequences in the diagnosis and treatment of diseases involving the abnormal expression of FGF-BP, such as cancers expressing FGF-BP, are also described. The sequences and methods are also useful to promote angiogenesis, to facilitate wound healing and in other applications.