| 发明名称 |
ANTI-CCR2 ANTIBODIES AND METHODS OF USE THEREFOR |
| 摘要 |
<p>The present invention relates to an antibody or functional fragment thereof which binds to a mammalian (e.g., human) CC-chemokine receptor (2) (CCR2) or a portion of the receptor and blocks binding of a ligand to the receptor. The invention further relates to a method of inhibiting the interaction of a cel l bearing mammalian CCR2 with a ligand thereof, and to use of the antibodies a nd fragments in therapeutic, prophylactic and diagnostic methods.</p> |
| 申请公布号 |
CA2336250(A1) |
申请公布日期 |
2000.02.03 |
| 申请号 |
CA19992336250 |
申请日期 |
1999.07.22 |
| 申请人 |
MILLENNIUM PHARMACEUTICALS, INC. |
发明人 |
LAROSA, GREGORY J.;HORVATH, CHRISTOPHER;NEWMAN, WALTER |
| 分类号 |
G01N33/53;A61K39/395;A61P9/10;A61P29/00;A61P31/18;A61P37/02;A61P43/00;C07K16/00;C07K16/28;C12N5/10;C12N15/02;C12N15/09;C12P21/08;C12Q1/02;C12R1/91;G01N33/566;G01N33/577;(IPC1-7):C07K16/28 |
主分类号 |
G01N33/53 |
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