| 发明名称 |
1,4-SUBSTITUTED CYCLIC AMINE DERIVATIVES |
| 摘要 |
<p>A novel 1,4-substituted cyclic amine derivative represented by the following formula or a pharmacologically acceptable salt thereof: <CHEM> (wherein A, B, C, D, T, Y and Z represent each methine or nitrogen; R<1>, R<2>, R<3>, R<4> and R<5> represent each a substituent; n represents 0 or an integer of 1 to 3; m represents 0 or an integer of 1 to 6; and p represents an integer of 1 to 3.) The compound has a serotonin antagonism and is clinically useful as medicament, in particular, for treating, ameliorating and preventing spastic paralysis or central muscle relaxants for ameliorating myotonia.</p> |
| 申请公布号 |
EP0976732(A1) |
申请公布日期 |
2000.02.02 |
| 申请号 |
EP19980911137 |
申请日期 |
1998.03.31 |
| 申请人 |
EISAI CO., LTD. |
发明人 |
KITAZAWA, NORITAKA;UENO, KOHSHI;TAKAHASHI, KEIKO;KIMURA, TEIJI;SASAKI, ATSUSHI;KAWANO, KOKI;OKABE, TADASHI;KOMATSU, MAKOTO;MATSUNAGA, MANABU;KUBOTA, ATSUHIKO |
| 分类号 |
C07D211/22;A61K31/135;A61P21/02;C07D211/26;C07D211/74;C07D217/02;C07D217/04;C07D221/04;C07D295/08;C07D295/10;C07D295/18;C07D401/04;C07D401/14;C07D403/04;C07D405/14;C07D417/14;C07D491/04;C07D491/056;C07D513/04;C07D521/00;(IPC1-7):C07D211/22;A61K31/435;A61K31/40;C07D471/04;C07D409/14;C07D295/12;A61K31/445;A61K31/47;A61K31/495;A61K31/55;A61K31/535 |
主分类号 |
C07D211/22 |
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