Gene and protein involved in liver regeneration

摘要

Gene involved in regeneration processes of the liver and comprising a nucleotide sequence which is at least 70% homologous to the sequence of figure 1, or the complementary strand thereof, for use in the design of PCR probes for detecting nucleotide sequences in a source material, which nucleotide sequences represent genes corresponding with the gene sequence of figure 1; protein encoded by said gene for use in diagnosis of liver regeneration and/or liver cell proliferation; and antibodies directed against this protein, a PCR primer comprising at least part of said gene as a probe, and a single stranded nucleotide sequence being at least in part complementary to the messenger RNA transcribed from said gene as a probe, for use in a method for detecting the occurrence of liver cell proliferation in a subject.