| 摘要 |
The nucleic acid sequence encoding the gene for the DNA polymerase I enzyme of Treponema pallidum, the organism causing syphilis. Nucleic acid molecules useful as probes for detecting Treponema pallidum are described. Isolated, recombinant, and synthetic DNA polymerase I enzyme of Treponema pallidum, and the amino acid sequence of the enzyme, are also described. Antibodies to DNA polymerase I from Treponema pallidum are further provided. The nucleic acid molecules are useful in methods for the detection and diagnosis of Treponema pallidum infection in a sample or subject.
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