| 摘要 |
PCT No. PCT/US96/06708 Sec. 371 Date May 5, 1997 Sec. 102(e) Date May 5, 1997 PCT Filed May 9, 1996 PCT Pub. No. WO96/35689 PCT Pub. Date Nov. 14, 1996Disclosed are compounds of formula (I), wherein Ar represents an aryl or heteroaxyl group; and R1, R2, R3, R4 and R5 represent organic or inorganic substituents, which compounds are highly selective partial agonists or antagonists at human CRF1 receptors and, thus, are useful in the diagnosis and treatment of treating stress related disorders such as post traunatic stress disorder (PTSD) as well as depression, headache and anxety.
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