摘要 |
PCT No. PCT/JP98/02081 Sec. 371 Date Jan. 11, 1999 Sec. 102(e) Date Jan. 11, 1999 PCT Filed May 12, 1998 PCT Pub. No. WO98/51680 PCT Pub. Date Nov. 19, 1998An industrial method for preparation of a 1,4-benzodioxane derivative (1), which comprises reacting a diol compound (2) with a carbonating agent to prepare a carbonate compound (3) and after removal of the protective group, cyclizing it by heating or by treating with a base or a fluoride salt.
|