发明名称 |
SYNTHETIC PEPTIDES FOR THE TREATMENT OF MYASTHENIA GRAVIS. |
摘要 |
<p>Peptides having at least nine amino acid residues each including an amino acid sequence which corresponds to position p200-208 or p262-266 of the human acetylcholine receptor (alpha)-subunit, but differing therefrom by one or more amino acid substitutions, are disclosed. These peptides inhibit the proliferative response of human peripheral blood lymphocytes to the myasthogenic peptides p195-212 and p259-271 and are suitable for treatment of subjects afflicted with myasthenia gravis.</p> |
申请公布号 |
GR3031371(T3) |
申请公布日期 |
2000.01.31 |
申请号 |
GR19990402465T |
申请日期 |
1999.09.29 |
申请人 |
YEDA RESEARCH AND DEVELOPMENT COMPANY, LTD. |
发明人 |
SELA, MICHAEL;MOZES, EDNA |
分类号 |
A61K38/00;A61K38/17;A61K39/00;A61P37/00;A61P43/00;C07K;C07K7/08;C07K14/705;(IPC1-7):A61K39/00;C07K7/00 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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