Microbiological preparation of 5-cetogluconate

摘要

Prodn. of 5-ketogluconate (I), comprises increasing the expression of the gluconate:NADP<+>-5-oxidoreductase (A) gene. Also new are: (1) Gluconobacter oxydans (A) gene (the 1512 bp nucleic acid sequence of which, and the 256 residue amino acid sequence encoded by it, are given in the specification), including its allelic variants; (2) gene structures and vectors contg. the gene of (1); and (3) transformed cells contg. the gene of (1), or the gene structures or vector of (2).