发明名称 AMIDE DERIVATIVES AND THEIR THERAPEUTIC USE
摘要 <p>PCT No. PCT/GB95/01040 Sec. 371 Date Nov. 8, 1996 Sec. 102(e) Date Nov. 8, 1996 PCT Filed May 9, 1995 PCT Pub. No. WO95/30645 PCT Pub. Date Nov. 16, 1995A compound of formula (I), wherein R1 and R2 are independently selected from chloro, fluoro, bromo, C1-6 alkyl, C1-6 alkoxy or C1-6 haloalkyl provided that both R1 and R2 are not fluoro; R3 and R4 are independently selected from hydrogen and C1-6 alkyl, and pharmaceutically acceptable salts, solvates or physiologically functional derivatives thereof, their use in medicine, particularly the phrophylaxis or treatment of conditions associated with inflammation, arthritis, or pain, pharmaceutical compositions comprising them, and processes for their preparation are disclosed. <IMAGE> (I)</p>
申请公布号 GR3031458(T3) 申请公布日期 2000.01.31
申请号 GR19990402549T 申请日期 1999.10.07
申请人 THE WELLCOME FOUNDATION LIMITED 发明人 MUSSO, DAVID, LEE;KELLEY, JAMES, LEROY
分类号 A61K31/165;A61K31/24;A61P25/04;A61P29/00;C07C;C07C17/14;C07C45/46;C07C53/136;C07C53/23;C07C57/42;C07C57/58;C07C57/60;C07C57/62;C07C57/76;C07C59/48;C07C59/54;C07C59/56;C07C59/64;C07C69/65;C07C69/732;C07C231/02;C07C231/12;C07C233/11;C07C235/34;(IPC1-7):C07C233/11 主分类号 A61K31/165
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