NOVEL 9-HYDROXY-PYRIDO [1,2-a]PYRIMIDIN-4-ONE ETHER DERIVATIVES

摘要

PCT No. PCT/EP94/03804 Sec. 371 Date May 3, 1996 Sec. 102(e) Date May 3, 1996 PCT Filed Nov. 16, 1994 PCT Pub. No. WO95/14691 PCT Pub. Date Jun. 1, 1995The present invention is concerned with novel compounds having the formula (I) the pharmaceutically acceptable acid addition salts thereof and the stereochemically isomeric forms thereof, wherein Alk represents C1-4alkanediyl; D is a bicyclic heterocycle of formula (a) orC2-6alkenyl; C2-6alkynyl; C3-6cycloalkyl optionally substituted with C1-4alkyl; C1-19alkyl optionally substituted with C3-6cycloalkyl, halo, C1-6alkyloxy or cyano; and each R2 independently is hydrogen or C1-4alkyl. Novel compounds; compositions; processes for preparing novel compounds and intermediates are described.