| 发明名称 |
Production of biologically active, recombinant members of the NGF/BDNF family of neurotrophic proteins |
| 摘要 |
<p>This invention describes processes for producing mature human members of the NGF/BDNF family of neurotrophic proteins that are fully biologically active. In addition, the gene encoding human BDNF and human BDNF are disclosed. A previously-unreported member of the NGF/BDNF family of neurotrophic proteins, NGF-3, has been identified and a portion of the gene encoding for the NGF-3 has been described. <IMAGE></p> |
| 申请公布号 |
GR3031632(T3) |
申请公布日期 |
2000.01.31 |
| 申请号 |
GR19990402673T |
申请日期 |
1999.10.21 |
| 申请人 |
AMGEN INC. |
发明人 |
COLLINS, FRANK D.;LILE, JACK;BEKTESH, SUSAN;MISMER, DRZISLAV;KOHNO, TADAHIKO |
| 分类号 |
A61K38/00;A61P25/28;C07K14/475;C07K14/48;C07K14/50;C12N15/09;C12N15/12;C12N15/70;C12Q1/68;C12R1/32;(IPC1-7):C12N15/12;C12P21/02;A61K38/18 |
主分类号 |
A61K38/00 |
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