发明名称 |
3,4-Disubstituted phenylethanolaminotetralincarboxamide derivatives |
摘要 |
3,4-Disubstituted phenylethanolaminotetralincarboxamide derivatives represented by general formula (I) and their pharmacologically acceptable salts having a selective 'beta'2-adrenergic receptor stimulating effect with a relieved burden on the heart such as frequent pulse. In said formula, A represents lower alkylene; B represents amino, di(lower alkyl)amino or 3- to 7-membered alicyclic amino optionally containing oxygen in the ring; n is an integer of 1 or 2; the carbon atom marked with "*" means a carbon atom or the R- or S- configuration or a mixture thereof; and the carbon atom marked with "(S)" means a carbon atom of the S-configuration. These compounds are useful as a preventive for threatened abortion/premature birth, a bronchodilator and a pain-relieving and lithagogue agent in ureterolithiasis.
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申请公布号 |
NZ331445(A) |
申请公布日期 |
2000.01.28 |
申请号 |
NZ19970331445 |
申请日期 |
1997.02.18 |
申请人 |
KISSEI PHARMACEUTICAL COMPANY LTD |
发明人 |
KITAZAWA, MAKIO;OKAZAKI, KOUSUKE;TAMAI, TETSURO;SAITO, MASARU;TANAKA, NOBUYUKI;KOBAYASHI, HIROAKI;KIKUCHI, KEN;MURANAKA, HIDEYUKI |
分类号 |
C07C235/06;C07D295/185;(IPC1-7):A61K31/535;C07D295/18;A61K31/165;A61K31/445;A61K31/495 |
主分类号 |
C07C235/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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