摘要 |
he present invention relates to a cascade polymer complex of the general formula 1 A-{X-[Y-(Z-(W-Kw)z)y]s}a A is a nitrogen containing nucleus of base multiplicity a X and Y independently stand for a direct bond or a cascade reproduction unit of reproduction multiplicity x or y Z and W independently stand for a cascade reproduction unit of reproduction multiplicity z or w, K is a radical of a complexing agent a is 2-12 x, y, z and w are 1-4 independently provided that at least two reproduction units are different and that for the product of the multiplicities, 16 ú a.x.y.z.wú64 holds true, and that at least one of cascade reproduction units X, Y, Z and W stands for a 1,4,7,10-tetraazacyclododecane reproduction unit or a 1,4, 8,11-tetraazacyclotetradecane reproduction unit. Also claimed is a pharmaceutical comprising the cascade polymer and use for NMR diagnosis.
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