Diglycosylated 1,2-diols as mimetics of sialyl-lewis x and sialyl-lewis a

摘要

ompounds of formula (I) in which X is the residue of a non-glycosidic aliphatic 1,2-diol; R1 is an S-configurated methyl substituted with one carboxyl residue and one other substituent; R2 is hydrogen, C1-C12alkyl or C6aryl; as mimetics of sialyl-Lewis X and sialyl-Lewis A. Also claimed is the preparation of compounds of formula (I) and their use as a pharmaceutical composition in the treatment of inflammation.