发明名称 Process for making imidazole derivatives with 4-aryl, 5-pyrimidine heterocycle rings
摘要 he application relates to a method for synthesizing imidazole derivatives having 4-aryl, 5-pyrimidine heterocyclic rings of the formula 1 using cycloaddition reaction. R1 is optionally substituted pyrimidin-4-yl ring; R4 is optionally substituted phenyl, naphth-1-yl or naphth-2-yl or heteroaryl ring; m is 0,1, or 2 m' is an integer having a value of 1 or 2; R2 is defined in the specification. Also claimed are compounds of the formula VIII, VI where the substituents are defined in the specification.
申请公布号 NZ326574(A) 申请公布日期 2000.01.28
申请号 NZ19960326574 申请日期 1996.12.20
申请人 SMITHKLINE BEECHAM CORPORATION 发明人 SISKO, JOSEPH
分类号 C07D401/04;C07D401/14;C07D403/04;C07D403/14;C07D413/14;(IPC1-7):C07D401/14 主分类号 C07D401/04
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