发明名称 COMPOSITIONS AND METHODS OF TREATING ABNORMAL CELL PROLIFERATION
摘要 A composition is described comprising a vitamin D analog and a retinoid wherein: (a) the vitamin D analog is capable of binding a vitamin D receptor or being converted in vivo into a compound capable of binding a vitamin D receptor; and (b) the retinoid is selected from the group consisting of retinol in a concentration of at least about 1.0 %, a compound in a concentration of at least about 1.0 % capable of being converted in vivo int o retinol, and a retinoid characterized by having a substitution at the 4- position. Further, methods of treating disorders characterized by abnormal cell-proliferation and/or cell-differentiation are also described.
申请公布号 CA2337138(A1) 申请公布日期 2000.01.27
申请号 CA19992337138 申请日期 1999.07.13
申请人 ACHKAR, CHARLES C. 发明人 ACHKAR, CHARLES C.
分类号 A61K8/00;A61K31/07;A61K31/59;A61K45/06;A61P17/00;A61P17/06;A61P17/14;A61P43/00;A61Q5/00;A61Q7/00;A61Q19/00;(IPC1-7):A61K31/07;A61K31/595 主分类号 A61K8/00
代理机构 代理人
主权项
地址