发明名称 |
2,5-SUBSTITUTED BENZOLSULFONYLUREAS AND THIOUREAS, METHODS FOR THE PRODUCTION THEREOF, USE THEREOF AND PHARMACEUTICAL PREPARATIONS CONTAINING THE SAME |
摘要 |
The compounds of formula (I) act as inhibitors on ATP-sensitive potassium canals and are suitable for the treatment of cardio-vascular disorders, especially the treatment of arrhythmias, prevention of sudden death from hea rt disease or affect diminished contractility of the heart. The invention also relates to methods for producing compounds of formula (I), the use thereof a nd pharmaceutical preparations containing said compounds.
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申请公布号 |
CA2337397(A1) |
申请公布日期 |
2000.01.27 |
申请号 |
CA19992337397 |
申请日期 |
1999.07.03 |
申请人 |
AVENTIS PHARMA DEUTSCHLAND GMBH |
发明人 |
HEITSCH, HOLGER;GOGELEIN, HEINZ;ENGLERT, HEINRICH CHRISTIAN |
分类号 |
C07D333/18;A61K31/18;A61K31/381;A61K31/4402;A61K31/4418;A61K31/64;A61P9/00;A61P9/06;A61P43/00;C07C311/00;C07C311/58;C07C317/32;C07C323/67;C07C335/42;C07D213/40;C07D307/38;C07D307/52;C07D333/20;(IPC1-7):C07C335/42;A61K31/34;A61K31/38;A61K31/44 |
主分类号 |
C07D333/18 |
代理机构 |
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地址 |
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