| 发明名称 |
LYSINE BINDING FRAGMENTS OF ANGIOSTATIN |
| 摘要 |
The present invention concerns peptide fragments of angiostatin containing lysine-binding sites of angiostatin which can be used as anti-angiogenic agents for the treatment of cancer, diabetic retinopathy, rheumatoid arthritis, psoriasis, atherosclerotic plaque formation, and any disease process that involves angiogenesis. The lysine binding fragments are derived from kringles 1,2 and/or 4 of plasminogen.
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| 申请公布号 |
CA2337231(A1) |
申请公布日期 |
2000.01.27 |
| 申请号 |
CA19992337231 |
申请日期 |
1999.07.07 |
| 申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
JI, RICHARD-WEI-DONG;TRAIL, PAMELA A. |
| 分类号 |
C12N15/09;A61K38/48;A61P17/06;A61P27/00;A61P29/00;A61P35/00;C07K14/47;C07K19/00;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N9/68;(IPC1-7):A61K38/00;C07K14/00;C12N15/11;A61K35/14;C12N15/63 |
主分类号 |
C12N15/09 |
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