| 发明名称 |
MAMMALIAN GENES ENCODING 3'-5' EXONUCLEASE |
| 摘要 |
Genes encoding 3'-5' exonucleases have been isolated and identified. A human exonuclease independent of DNA polymerase is produced in host cells from recombinant vectors. Methods of use include inhibition of exonuclease activity to increase incorporation of nucleotide analogs into DNA in rapidly dividing cells.
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| 申请公布号 |
WO9961064(A8) |
申请公布日期 |
2000.01.27 |
| 申请号 |
WO1999US10578 |
申请日期 |
1999.05.14 |
| 申请人 |
WAKE FOREST UNIVERSITY;PERRINO, FRED, W. |
发明人 |
PERRINO, FRED, W. |
| 分类号 |
A61K38/00;A61P31/12;A61P35/00;C12N1/21;C12N9/22;(IPC1-7):A61K48/00;C07H21/04;C12N15/63;C12N15/86 |
主分类号 |
A61K38/00 |
| 代理机构 |
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代理人 |
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| 地址 |
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