发明名称 PYRIMIDINE DERIVATIVES EXHIBITING ANTITUMOR ACTIVITY
摘要 Compounds represented by general formula (I); prodrugs of the same; or pharmaceutically acceptable salts of both; or solvates of them. In said formula, R<1>, R<2>, R<3> and R<4> are each independently hydrogen, alkyl or the like; R<5> and R<6> are each independently hydrogen, alkyl or the like; X is -O-, -S- or the like; Y is a divalent group derived from a five-membered aromatic heterocycle, or the like; and Z is optionally substituted aryl or the like.
申请公布号 WO0004014(A1) 申请公布日期 2000.01.27
申请号 WO1999JP03863 申请日期 1999.07.16
申请人 SHIONOGI & CO., LTD.;UEDA, KAZUO;TANAKA, HIDEKAZU;TAKENAKA, HIDEYUKI 发明人 UEDA, KAZUO;TANAKA, HIDEKAZU;TAKENAKA, HIDEYUKI
分类号 C07D413/12;(IPC1-7):C07D403/12;C07D405/12;C07D413/14;C07D417/12;C07D417/14;A61K31/505 主分类号 C07D413/12
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